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Moss Report on Non-Hodgkin’s Lymphoma: Follicular (FL)

Alternative & Conventional Non-Hodgkin’s Lymphoma: Follicular (FL) Treatments (2019 Update)

The Moss Reports on lymphoma (cancers of the lymphatic system) brings you a thorough and up-to-date discussion of the best results with radiation therapy, chemotherapy, immunotherapy, integrative, complementary and alternative treatments for different types of lymphoma.

We have separate Moss Reports on the following statistically important forms of lymphoma: (Make sure to order the one specific to the type of lymphoma you are dealing with.)

HODGKIN’S LYMPHOMA 

NON-HODGKIN’S LYMPHOMA – BURKITT’S (BL)

NON-HODGKIN’S LYMPHOMA – MANTLE CELL (MCL)

NON-HODGKIN’S LYMPHOMA – DIFFUSE LARGE B CELL (DLBCL)

NON-HODGKIN’S LYMPHOMA – MYCOSIS FUNGOIDES (CLTCL)

NON-HODGKIN’S LYMPHOMA – FOLLICULAR  (this page)

What’s New In Lymphoma Treatment

James Allison, PhD, is the head of immunology at the University of Texas M.D. Anderson Cancer Center, Houston. While at the University of California, Berkeley, he invented an important new class of medications called “immune checkpoint inhibitors.” Allison is currently working on combining these medications with cancer-killing viruses, such as Newcastle Disease Virus (NDV) vaccines. These are already available at several foreign clinics.One of the most significant advances of recent years has been the development and FDA approval of an anti-cancer virus vaccine, Reolysin® (pelareorep). The 2019 Moss Report discusses this new medicine and its associated clinical trials., and the use of adoptive immunotherapy against blood system cancers, including lymphoma.

Lymphoma Treatment

Lymphoma is cancer that originates in and mainly affects the lymphatic system. When fluid enters and moves in these vessels it is named lymph. The lymphatic system is one of the 13 basic systems of the body: it is little appreciated when it is functioning well, in fact we are hardly conscious of its existence.  You generally only become aware of its existence when you get “swollen glands” from an infection or when, much more rarely, when you develop a cancer that affects the lymphocytes (the characteristic blood cells that inhabit this system). Lymph is the fluid that circulates in the lymphatic system, whose fundamental purpose is to transport fluid to the parallel blood system, to eliminate wastes, and to fight infections.

Within this network of lymphatic vessels there are “filters,” called lymph nodes. Each of us has about 800 of these bean-shaped nodes or “glands.” These are strategically positioned in the middle of the chest, as well as neck, armpits, groin, pelvis and gut. Anatomically, the lymphatic system is complex. In addition to the vessels and nodes, there are other depots of lymphatic tissue throughout the body. These include the spleen, which is like one giant lymph node. In addition, patches of lymphoid tissue are located in the skin, throughout the mucosal lining of the respiratory tract (nose, mouth, throat, airways and lungs) and in the gastrointestinal tract (esophagus, stomach, small and large bowel, rectum and anus). These GI tract lymphatic areas have a special name: Peyer’s patches (named for a Swiss anatomist of the Renaissance era). And of course the bone marrow is rich in lymphoid tissue, since it is here that the immune cells (lymphocytes) are actually produced.

In order to make sense of the various classification systems, and therefore of the daunting array of diagnostic and therapeutic possibilities, it is important first of all to have a basic understanding of the origins of the disease. 

Lymphocytes are the white blood cells (WBCs) that form the basis of the immune system. There are three major kinds of lymphocytes: B cells, T cells and NK cells. These cells originate in the bone marrow, but while B cells grow to maturity in the bone marrow, T cells normally migrate from the marrow while they are still immature and only mature after they reach the thymus gland (a little known organ that in humans resides behind the breast bone). In adults, 85 to 90 percent of all lymphomas are of the B-cell variety, while only 15 percent are derived from thymus-conditioned T-cells.

You and your doctor will need to know whether your NHL originates in a B-cell, T-cell or NK-cell. Each of these is a subtype of a kind of white blood cell called a lymphocyte. And each of these, says the American Society of Clinical Oncology (ASCO), “can behave differently and may require different treatments.”

There is Hodgkin’s or a non-Hodgkin’s lymphoma, an indolent or an aggressive type, and a B-cell, T-cell or NK-cell lymphoma. In fact you are only just beginning to define your condition, for there are 35 or so subtypes of NHL which can also affect treatment decisions.  Each of these is identified through various stains, cell surface markers, genetic abnormalities, etc.

We have written Moss Reports that go into depth on the Hodgkin’s lymphoma and five of the most common forms of non-Hodgkin’s lymphoma. Our goal is to take an extremely complicated topic and make it comprehensible to the patient and his or her family.

Moss Reports e-book Alternative Cancer Therapies

Moss Report
Non-Hodgkin's Lymphoma
Follicular (FL)
E-book

$349

Moss Report printed icon Alternative Cancer Therapies

Moss Report
Non-Hodgkin's Lymphoma
Follicular (FL)
Printed Book

$379

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Table of Contents

  • A QUICK GUIDE TO CAM CANCER TREATMENTS
  • GREEN LIGHT TREATMENTS: WELL RESEARCHED APPROACHES
  • AMBER LIGHT TREATMENTS FOR CANCER: EFFICACY AND SAFETY STILL UNCLEAR
  • RED LIGHT TREATMENTS: POORLY RESEARCHED (OR DOWNRIGHT DANGEROUS)
  • CONVENTIONAL TREATMENT SECTION
  • BASICS
  • CANCERS OF THE LYMPHATIC SYSTEM
  • INCIDENCE AND CAUSES
  • TYPES
  • DEVELOPMENTAL STAGES
  • LOW-GRADE NHL
  • WATCH-AND-WAIT APPROACH
  • WATCH AND WAIT FOR ASYMPTOMATIC, ADVANCED-STAGE NHL
  • AGGRESSIVE LYMPHOMAS
  • TREATMENT OF NHL: AN OVERVIEW
  • THE USE OF PET-CT IN NHL
  • THE FDA-APPROVED DRUGS
  • OFF-LABEL USE
  • RITUXIMAB (RITUXAN®)
  • PIXANTRONE (PIXUVRI®)
  • CLASSIFYING NHL
  • FOLLICULAR LYMPHOMA (FL)
  • FL BASICS
  • WATCH AND WAIT IN FOLLICULAR LYMPHOMA (FL)
  • NCCN RECOMMENDATIONS
  • FIRST-LINE THERAPY: NCCN RECOMMENDATIONS
  • ADVANCED STAGE III OR IV INDOLENT NODAL LYMPHOMAS
  • DISCUSSION
  • OBINUTUZUMAB FOR PREVIOUSLY UNTREATED FOLLICULAR LYMPHOMA
  • THE PROBLEM OF SECOND CANCERS
  • NEW TREATMENTS
  • IBRITUMOMAB TIUXETAN (ZEVALIN®)
  • BIOVAXID
  • OTHER VACCINE THERAPY
  • EFFECT OF MEDICINAL MUSHROOMS ON NHL
  • OTHER DEVELOPMENTS
  • ADOPTIVE IMMUNOTHERAPY (CAR-T CELL)
  • TOP SUPPLEMENTS (THE SHORT LIST)
  • ANTI-CANCER PLAN ON A TIGHT BUDGET
  • ANTI-CANCER RECIPES
  • THE HALLMARKS OF CANCER
  • A NEW MODEL FOR CANCER TREATMENT
  • INNOVATIVE SURGERY
  • INNOVATIVE RADIATION THERAPY
  • INNOVATIVE CHEMOTHERAPY
  • NAUSEA AND VOMITING
  • ACUPUNCTURE
  • BETA-GLUCANS
  • HYPNOSIS
  • MUSIC
  • MOUTH SORES (STOMATITIS)
  • ZINC SULFATE
  • NERVE PAIN
  • HAIR LOSS
  • CRAMPS
  • PICKLE JUICE REMEDY
  • CHEMOSENSITIVITY TESTING
  • TARGETED THERAPIES
  • PRECISION MEDICINE INITIATIVE
  • ANTI-ANGIOGENESIS DRUGS
  • MOLECULAR AND GENOMIC TESTING
  • CIRCULATING TUMOR CELLS (CELLSEARCH)
  • MONOCLONAL ANTIBODIES
  • IMMUNE CHECKPOINT BLOCKADE (ICB)
  • CANCER STEM CELLS (CSCS)
  • DIETARY COMPOUNDS THAT KILL CANCER STEM CELLS (CSCS)
  • PHYSICAL ACTIVITY AND EXERCISE
  • FASTING AND THE KETOGENIC DIET
  • A COST-FREE WAY TO PREVENT CANCER RECURRENCES
  • CALORIC RESTRICTION
  • PRACTICAL NOTES ON FASTING
  • TOP TEN SUPPLEMENTS (THE EXPOSITION)
  • FOOD AND CANCER PREVENTION
  • VITAMINS, MINERALS & ANTIOXIDANTS
  • THE CONCURRENT USE DEBATE
  • RADIOPROTECTION
  • CONCURRENT USE OF ANTIOXIDANTS AND RADIATION
  • HERBS, SPICES AND BOTANICALS
  • HYPERTHERMIA
  • CRYOABLATION
  • SOUND, LIGHT AND ELECTRICITY
  • CANCER IMMUNOTHERAPY
  • VIRAL THERAPY (ONCOLYTIC VIRUSES)
  • ELECTROACUPUNCTURE
  • DRUGS NEW AND OLD
  • INNOVATIVE CANCER CLINICS
  • FINDING AN INTEGRATIVE PHYSICIAN
  • INTEGRATIVE ONCOLOGY DEPARTMENTS
  • AMERICAN CLINICS
  • INTERNATIONAL CLINICSSUPPLEMENTS AND SURGERY
  • CAM AND FATIGUE
  • POPULAR BUT UNLIKELY TREATMENTS

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